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Anti-VEGF Injections for AMD

Anti-VEGF Injections for AMD

Anti-VEGF injections are used to treat certain forms of age-related macular degeneration by reducing abnormal blood vessel activity and helping to preserve central vision.
View VideoDescribes how intravitreal injections are injected into the vitreous to administer medications for retinal diseases such as macular degeneration, diabetic retinopathy, macular edema, and retinal vein occlusion. Shows the steps of the injection process, notes some common side effects, and advises on the frequency of re-treatments.
Anti-VEGF injections are a key treatment for certain forms of age-related macular degeneration, particularly those involving abnormal blood vessel growth. These injections are used to stabilise the macula and help preserve central vision.

What are anti-VEGF injections?

Anti-VEGF injections are medications delivered directly into the eye to target a substance known as vascular endothelial growth factor (VEGF). This substance plays a role in the development of abnormal blood vessels beneath the retina.

By blocking VEGF, these injections help reduce abnormal vessel growth and limit fluid leakage within the macula.

Why anti-VEGF treatment is used

In more active forms of age-related macular degeneration, abnormal blood vessels can disrupt the structure of the retina and lead to rapid changes in vision.

Anti-VEGF treatment is used to stabilise these changes and reduce further damage to the macula.

How the injections work

The medication works by inhibiting signals that promote abnormal blood vessel formation. This helps reduce leakage and swelling within the retina.

As a result, the structure of the macula can stabilise, supporting better visual function over time.

The procedure

Anti-VEGF injections are performed in a controlled clinical setting. The eye is carefully prepared, and the injection is administered using precise techniques.

The procedure is brief and designed to be as comfortable as possible.

Treatment schedule

Treatment often requires a series of injections over time rather than a single procedure. The frequency depends on how the eye responds and how the condition progresses.

Regular follow-up is essential to determine the appropriate treatment interval.

What to expect after treatment

After the injection, some mild discomfort or temporary visual disturbance may occur. These effects are usually short-lived.

Patients are monitored closely to assess response and detect any changes.

View VideoDetailed overview of what recovering intravitreal injection patients should expect following the surgery, including duration of recovery, symptoms of possible infection, and the possibility of further treatments.

Effectiveness of anti-VEGF treatment

Anti-VEGF injections are effective in stabilising vision in many cases and may help slow progression. The degree of improvement varies depending on the stage of the condition and how early treatment is started.

Importance of ongoing care

Consistent follow-up is essential to monitor the retina and determine whether further injections are required.

Ongoing care helps maintain stability and reduce the risk of further vision changes.

When to seek assessment

If you have been diagnosed with age-related macular degeneration or notice sudden changes in central vision, prompt assessment is important to determine whether treatment is required. If you would like to discuss anti-VEGF treatment or assess your eligibility, schedule a consultation with Dr Cronjé Ophthalmologist & Eye Surgeon | FC Ophth (SA) | MBChB (Pret) | Dip Ophth (SA) for expert evaluation and personalised care.